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- W2361479080 abstract "Objective:To investigate the expression of human leucocyte antigen protein G(HLA-G) in different histological grade and clinical TNM phase of colorectal cancer patients and to explore the role of HLA-G in tumor escape.Methods:The expression of HLA-G in normal colorectal tissues and colorectal cancer tissues was examined by immunohistochemistry, Kruskal-Wallis test in SPSS software versions 13.0 was used to analyze the statistical significance.Results:The positive expression rate of HLA-G was 42.3%(41 / 97) in colorectal cancer and 0(0 / 20) in normal colorectum.The expression of HLA-G was positively correlated with clinical TNM phase(P0.05) and histological grade(P0.01).Conclusion:The up-regulation expression of HLA-G associated with invasive growth of colorectal cancer implied that HLA-G might down-regulate the host's immunological response and thereby favour the immune escape of tumor cells." @default.
- W2361479080 created "2016-06-24" @default.
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- W2361479080 date "2009-01-01" @default.
- W2361479080 modified "2023-09-23" @default.
- W2361479080 title "Expression and Clinical Significance of Human Leucocyte Antigen Protein G in Colorectal Cancer" @default.
- W2361479080 hasPublicationYear "2009" @default.
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