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- W2361509969 abstract "Objective To explore the relationship between the resistance to activated protein C(APCR),serum concentrations of interleukins(IL-10,IL-12)and occurrence of unexplained recurrent abortion. Methods The resistance to activated protein C and serum concentrations of IL-10,IL-12 were measured in patients with unexplained recurrent abortion and controlled by APTT-APC and ELISA,respectively. Results Serum concentration of IL-12 and the positive rate of APCR in the unexplained recurrent abortion group were significantly higher than those in the control group,respectively(P0.01),but serum concentration of IL-10 in the patients was significantly lower than that in the controls.There was a negative correlation between IL-10 and IL-12(r=-0.672,P0.05). Conclusion The resistance to activated protein C plays an important role in the occurrence of the unexplained recurrent abortion.And when the serum concentration of IL-12 in the pregnant women was significantly increased and the level of serum IL-10 was significantly decreased,it leads to the occurrence of the unexplained recurrent abortion,since the immunity balance of venter-embryo was broken." @default.
- W2361509969 created "2016-06-24" @default.
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- W2361509969 date "2009-01-01" @default.
- W2361509969 modified "2023-09-23" @default.
- W2361509969 title "Relationship between Unexplained Recurrent Abortion and Resistance to Activated Protein C,Serum Concentrations of IL-10 and IL-12" @default.
- W2361509969 hasPublicationYear "2009" @default.
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