Matches in SemOpenAlex for { <https://semopenalex.org/work/W2361553539> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2361553539 abstract "Objective:Evaluate the effect of tranexamic acid with different application time on postoperative bleeding,fibrinolytic activity and platelet function in cardiac valve replacement with cardiopulmonary bypass.Methods:Forty-five patients with heart valve disease were randomly divided into three groups.Group TA-1 received 0.5 g tranexamic acid within 15 min at the beginning of cardiopulmonary bypass,followed by continuous infusion of another 0.5 g during cardiopulmonary bypass.Group TA-2 received 1.0 g tranexamic acid after the bypass.Group control received nothing during and after bypass.Cumulative blood loss at 6 h and 24 h,blood transfusion at 24 h,D-dimer level and platelet count at 6 h after surgery were recorded.Results:Postoperative blood loss and transfusion were significantly reduced in group TA-1 and TA-2 when compared with the control group.Group TA-1 has less blood loss at 6 h and 24 h than group TA-2.The blood transfusion was also less in group TA-1 than TA-2,however the difference was not significant.There was a significant increase in plasma D-dimer level at 6 h after surgery.Among the three groups,group TA-1 has the lowest D-dimer level,which is lower in group TA-2 than in the control group.Platelet count at 6 h after surgery was similarly reduced in the TA-2 group and control group,which was significantly less than that of TA-1 group.Conclusion:Tranexamic acid effectively reduces postoperative bleeding and blood transfusion in patients undergoing cardiac valve replacement with cardiopulmonary bypass compared to the control.Continuous application of tranexamic acid during the cardiopulmonary bypass has a better effect than a single dose after bypass on postoperative bleeding,blood transfusion,anti-fibrinolysis and platelet protection." @default.
- W2361553539 created "2016-06-24" @default.
- W2361553539 creator A5028364292 @default.
- W2361553539 creator A5030043250 @default.
- W2361553539 creator A5033687712 @default.
- W2361553539 creator A5035747390 @default.
- W2361553539 creator A5068303631 @default.
- W2361553539 creator A5076296494 @default.
- W2361553539 creator A5086350742 @default.
- W2361553539 date "2010-01-01" @default.
- W2361553539 modified "2023-09-28" @default.
- W2361553539 title "The optimal application time of tranexamic acid in the cardiac valve replacement with cardiopulmonary bypass to reduce postoperative bleeding" @default.
- W2361553539 hasPublicationYear "2010" @default.
- W2361553539 type Work @default.
- W2361553539 sameAs 2361553539 @default.
- W2361553539 citedByCount "0" @default.
- W2361553539 crossrefType "journal-article" @default.
- W2361553539 hasAuthorship W2361553539A5028364292 @default.
- W2361553539 hasAuthorship W2361553539A5030043250 @default.
- W2361553539 hasAuthorship W2361553539A5033687712 @default.
- W2361553539 hasAuthorship W2361553539A5035747390 @default.
- W2361553539 hasAuthorship W2361553539A5068303631 @default.
- W2361553539 hasAuthorship W2361553539A5076296494 @default.
- W2361553539 hasAuthorship W2361553539A5086350742 @default.
- W2361553539 hasConcept C126322002 @default.
- W2361553539 hasConcept C141071460 @default.
- W2361553539 hasConcept C164705383 @default.
- W2361553539 hasConcept C2778789114 @default.
- W2361553539 hasConcept C2778881276 @default.
- W2361553539 hasConcept C2779519742 @default.
- W2361553539 hasConcept C2779637338 @default.
- W2361553539 hasConcept C2780007028 @default.
- W2361553539 hasConcept C2780014101 @default.
- W2361553539 hasConcept C2780026749 @default.
- W2361553539 hasConcept C2991743468 @default.
- W2361553539 hasConcept C42219234 @default.
- W2361553539 hasConcept C71924100 @default.
- W2361553539 hasConcept C89560881 @default.
- W2361553539 hasConceptScore W2361553539C126322002 @default.
- W2361553539 hasConceptScore W2361553539C141071460 @default.
- W2361553539 hasConceptScore W2361553539C164705383 @default.
- W2361553539 hasConceptScore W2361553539C2778789114 @default.
- W2361553539 hasConceptScore W2361553539C2778881276 @default.
- W2361553539 hasConceptScore W2361553539C2779519742 @default.
- W2361553539 hasConceptScore W2361553539C2779637338 @default.
- W2361553539 hasConceptScore W2361553539C2780007028 @default.
- W2361553539 hasConceptScore W2361553539C2780014101 @default.
- W2361553539 hasConceptScore W2361553539C2780026749 @default.
- W2361553539 hasConceptScore W2361553539C2991743468 @default.
- W2361553539 hasConceptScore W2361553539C42219234 @default.
- W2361553539 hasConceptScore W2361553539C71924100 @default.
- W2361553539 hasConceptScore W2361553539C89560881 @default.
- W2361553539 hasIssue "10" @default.
- W2361553539 hasLocation W23615535391 @default.
- W2361553539 hasOpenAccess W2361553539 @default.
- W2361553539 hasPrimaryLocation W23615535391 @default.
- W2361553539 hasRelatedWork W175916249 @default.
- W2361553539 hasRelatedWork W2003347844 @default.
- W2361553539 hasRelatedWork W2006297479 @default.
- W2361553539 hasRelatedWork W2279620341 @default.
- W2361553539 hasRelatedWork W2302214724 @default.
- W2361553539 hasRelatedWork W2407910548 @default.
- W2361553539 hasRelatedWork W2416848411 @default.
- W2361553539 hasRelatedWork W2425888134 @default.
- W2361553539 hasRelatedWork W2724764719 @default.
- W2361553539 hasRelatedWork W2895713455 @default.
- W2361553539 hasRelatedWork W2937787021 @default.
- W2361553539 hasRelatedWork W3023531576 @default.
- W2361553539 hasRelatedWork W3028869493 @default.
- W2361553539 hasRelatedWork W3028965959 @default.
- W2361553539 hasRelatedWork W3029478951 @default.
- W2361553539 hasRelatedWork W3030114549 @default.
- W2361553539 hasRelatedWork W3030344406 @default.
- W2361553539 hasRelatedWork W3031728258 @default.
- W2361553539 hasRelatedWork W3032066030 @default.
- W2361553539 hasRelatedWork W3117064220 @default.
- W2361553539 isParatext "false" @default.
- W2361553539 isRetracted "false" @default.
- W2361553539 magId "2361553539" @default.
- W2361553539 workType "article" @default.