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- W2361567800 abstract "Objective To investigate the potential of bone marrow mesenchymal-derived stem cells(MSCs) in treatment of calvarial defect.Methods Mice MSCs were isolated and cultured in osteoinductive medium.Calvarial bone defects about 5.0 mm×5.0 mm were made on each of the same litter of mice,then filled with none(control group),or calcinated bone and alginate calcium(vehicle group),or MSCs plus calcinated bone and alginate sodium(experimental group).All specimens were removed 4 months post-transplantation for histological evaluation.Results No bone was observed in defects without restoration.A few of new bones were found in defects in vehicle group.Many newly formed bone connected with the end of host bone were also found in defects repaired with MSCs with calcinated bone and alginate sodium.Conclusion MSCs with calcinated bone and alginate sodium have the potential for repairing bone defects." @default.
- W2361567800 created "2016-06-24" @default.
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- W2361567800 date "2010-01-01" @default.
- W2361567800 modified "2023-09-28" @default.
- W2361567800 title "Experiment Study of the Potential of Bone Marrow-derived Mesenchymal Stem Cells in Restoration of Mouse Calvarial Defects" @default.
- W2361567800 hasPublicationYear "2010" @default.
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