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- W2361569257 abstract "Objective The study was to examine the role of serum pyridinoline-cross-linked carboxyterminal telopeptide of type I collagen(I CTP) and bone-specific alkaline phosphatase(B-AKP) in the diagnosis of metastatic bone cancer.Method The serum of 49 metastatic bone cancer patients,56 cancer patients without bone metastases and 50 normal individuals were collected.The levels of ⅠCTP and B-AKP of the serum collected were quantitatively determined.Results TheⅠCTP level and B-AKP level in cancer patients with bone metastasis were significantly higher than that of those patients without bone metastasis and the normal individuals.There were no difference in serum ⅠCTP level and B-AKP level between patients without bone metastasis and normal individuals.The sensitivity and specificity of combined detection of ⅠCTP and B-AKP was 91.8% and 88.0% for cancer patients with bone metastasis.Conclusion The combined detection of the serum ⅠCTP and B-AKP level would receive the desirable sensitivity and play an important role in the diagnosis of bone metastases of cancer patients." @default.
- W2361569257 created "2016-06-24" @default.
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- W2361569257 date "2013-01-01" @default.
- W2361569257 modified "2023-09-27" @default.
- W2361569257 title "The effects of serum pyridinoline-cross-linked carboxyterminal telopeptide of type I collagen and bone-specific alkaline phosphatase on metastatic bone cancer" @default.
- W2361569257 hasPublicationYear "2013" @default.
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