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- W2361623967 abstract "Objective: To detect the expression of p16,nm23H1 in malignant lymphoma cells and to elucidate its relation to the clinicopathological characteristics,chemotherapeutic response and survival rate,and therefore to provide a new theoretical basis for clinical treatment and predicting prognosis.Methods: Immunohistochemical technique,S-P method was used.Results: 1.There is not statistically significant difference between the expression of p16,nm23H1 in HL and that in NHL($P$0.05).2.The expression of p16 was weakened,while the expression of nm23H1 was enhanced with the increase in the level of malignancy in NHL($P$0.01).3. The CR rate in patients with high expression of p16 was far better than that in patients with low expression of p16($P$0.05);the CR rate in patients with high expression of nm23H1 was far worse than that in patients with low expression of nm23H1($P$0.05).4.The difference of survival rate between the group with p16 high expression and that with p16 low expression was not significant($P$0.05);the survival rate in the group with nm23H1 low expression was significantly higher than that in the group with nm23H1 high expression($P$0.01).Conclusion: p16,nm23H1 expression levels in malignant lymphoma can not only reflect its level of malignancy but also predict the prognosis." @default.
- W2361623967 created "2016-06-24" @default.
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- W2361623967 date "2006-01-01" @default.
- W2361623967 modified "2023-09-24" @default.
- W2361623967 title "THE EXPRESSION OF p16, nm23H1 IN LYMPHOMA AND THE CLINICAL MEANING" @default.
- W2361623967 hasPublicationYear "2006" @default.
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