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- W2361657800 abstract "OBJECTIVE To research the significance of S100 protein in the evaluation of postoperative cognitive dysfunction after cardiopulmonary bypass(CPB).METHODS Sixty-four patients who had been scheduled to receive cardiac valve replacement were selected.The level of serum S100 protein was measured 5 min before CPB(T1),30 min after CPB(T2),at the end of CPB(T3),6 h(T4),24 h(T5)and 48 h(T6)after surgery.A battery of 9 neuropsychological tests was performed and scored preoperatively and 9 days after surgery.Newman's criterion was used to decide whether patients had happened postoperative cognitive dysfunction,and then divided patients into normal group(group A)and cognitive dysfunction group(group B)for control study.RESULTS Both preoperative and postoperative neuropsychological tests were completely performed for sixty-tow patients.The incidence rate of postoperative cognitive dysfunction was 48.4%(30/62 cases).During CPB,the level of serum S100 protein of two groups was higher than that before CPB(P0.01).Compared with group A,the level of group B's serum S100 protein was significant higher at all times(P0.01)exclude T1.CONCLUSION The level of serum S100 protein is very valuable for monitoring postoperative cognitive dysfunction after CPB." @default.
- W2361657800 created "2016-06-24" @default.
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- W2361657800 date "2009-01-01" @default.
- W2361657800 modified "2023-09-26" @default.
- W2361657800 title "The Significance of S100 Protein in the Evaluation of Postoperative Cognitive Dysfunction after Cardiopulmonary Bypass" @default.
- W2361657800 hasPublicationYear "2009" @default.
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