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- W2361700939 abstract "OBJECTIVE To explore the clinical features of Langerhans cell histiocytosis(LCH)in children.METHODS 57 cases of LCH from were collected from inpatient department of our hospital.The features of clinic,pathology and immunohistochemistry were analyzed.RESULTS The mean age of onset was 2.34 years old.The male/female ratio was 1.48:1.Skin lesions occurred in 50.88% of the patients.The eruptions mainly distributed on trunk and head,some of them presented as hemorrhagic maculopapules,sebaceous flux erythra and papular eruption.Other of the eruptions showed as emphlysis and incontinence of pigmentation.Fever and hepatosplenomegia occurred in patients with a rate of 54.39% and 56.14%,respectively.31.58% of the patients had got lymphadenectasis,the neck and inguinal lymph nodes were the common site to be affected.Ossature involvement occurred in 24.56% of the patients.Skull was the main site to be injured,and the others were clavicula,limbs bones and so on.CONCLUSION Multiple systems can be involved in LCH of children.After the comparison between presentation of different age children,we found rash was more common presentation in younger group,and there was no difference between two groups of other clinical features." @default.
- W2361700939 created "2016-06-24" @default.
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- W2361700939 date "2012-01-01" @default.
- W2361700939 modified "2023-09-22" @default.
- W2361700939 title "Clinical analysis of Langerhans cell histiocytosis(LCH) in 57 children" @default.
- W2361700939 hasPublicationYear "2012" @default.
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