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- W2361750786 abstract "Objective:To study the influence of flunarizine hydrochloride on the content of the plasma endothelin(ET) in patients with subarachnoid hemorrhage(SAH) and discuss the mechanism of flunarizine hydrochloride in the prevention and treatment of cerebral vasospasm (CVS) after SAH. Method:44 cases of SAH were divided into flunarizine hydrchloride group (20 cases) and SAH control group (24 cases) randomly. Radioimmuno assay was used to measure the content of plasma ET at different times. Results:The content of plasma ET in flunarizine hydrochloride group was compared with those in SAH control group and nomal control group ( P 0.01 , P 0.05) at different times. After treatment with flunarizine hydrchloride, the content of plasma ET in flunarizine hydrochloride group was significantly lower than that in SAH control group ( P 0.01, P 0.05), and it was also significantly lower than that in flunarizine hydrochloride group before treatment ( P 0.01). Conclusion:Flunarizine hydrochloride can prevent and treat the CVS after SAH, and ensure the blood supply of cerebral tissues by decreasing the content of plasma ET." @default.
- W2361750786 created "2016-06-24" @default.
- W2361750786 creator A5058514098 @default.
- W2361750786 date "2003-01-01" @default.
- W2361750786 modified "2023-09-28" @default.
- W2361750786 title "Influence of Flunarizine Hydrochloride on Plasma Endothelin in Patients with Subarachnoid Hemorrhage" @default.
- W2361750786 hasPublicationYear "2003" @default.
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