Matches in SemOpenAlex for { <https://semopenalex.org/work/W2361776515> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2361776515 abstract "OBJECTIVE:To evaluate the efficacy and safety of Mannatide injection in the treatment of malignant pleural effusion systematically.METHODS:Literatures were retrieved from Cochrane Library,Medline,Embase,CNKI,VIP,CBM,databases by computer and from conference papers and thesis by hand.Randomized/quasi-randomized control trials about mannatide in the treatment of malignant pleural effusion were collected.Trial selection,quality evaluation and information extraction were performed according to including and excluding criteria.Meta-analysis was conducted using RevMan 5.0 software.RESULTS:17 RCTs were included and divided into three sub-groups.Results of Meta-analysis showed:Sub-group A and B were better than control [RR=1.38,95%CI(1.27,1.50),P0.01],[RR=1.34,95%CI(1.17,1.54),P0.01],there was significant difference between two sub-groups.KPS score of trial group was better than control group [RR=1.82,95%CI(1.51,2.20),P0.01].Survival duration of trial group was better than control group (P0.05).Adverse drug reactions:results of 17 studies showed that mannatide could reduce myelosuppression,gastrolntestinal reaction and pectoralgia caused by platinum antitumor drugs while mannatide maybe cause slight fever.CONCLUSION:Mannatide combination can improve short-term efficacy of platinum antitumor drugs reduce adverse drug reactions and improve life quality while it can induce slight fever.However,due to the limited quality of included studies and publication bias,further study is required through large-scale high-quality and multi-centre randomized double-blind control trials." @default.
- W2361776515 created "2016-06-24" @default.
- W2361776515 creator A5055309139 @default.
- W2361776515 date "2011-01-01" @default.
- W2361776515 modified "2023-09-26" @default.
- W2361776515 title "Systematic Review of Platinum Antitumor Drugs Combined with Mannatide in the Treatment of Malignant Pleural Effusion" @default.
- W2361776515 hasPublicationYear "2011" @default.
- W2361776515 type Work @default.
- W2361776515 sameAs 2361776515 @default.
- W2361776515 citedByCount "0" @default.
- W2361776515 crossrefType "journal-article" @default.
- W2361776515 hasAuthorship W2361776515A5055309139 @default.
- W2361776515 hasConcept C126322002 @default.
- W2361776515 hasConcept C168563851 @default.
- W2361776515 hasConcept C197934379 @default.
- W2361776515 hasConcept C2776232967 @default.
- W2361776515 hasConcept C2776478404 @default.
- W2361776515 hasConcept C2779634585 @default.
- W2361776515 hasConcept C2780035454 @default.
- W2361776515 hasConcept C2993432071 @default.
- W2361776515 hasConcept C71924100 @default.
- W2361776515 hasConcept C95190672 @default.
- W2361776515 hasConcept C98274493 @default.
- W2361776515 hasConceptScore W2361776515C126322002 @default.
- W2361776515 hasConceptScore W2361776515C168563851 @default.
- W2361776515 hasConceptScore W2361776515C197934379 @default.
- W2361776515 hasConceptScore W2361776515C2776232967 @default.
- W2361776515 hasConceptScore W2361776515C2776478404 @default.
- W2361776515 hasConceptScore W2361776515C2779634585 @default.
- W2361776515 hasConceptScore W2361776515C2780035454 @default.
- W2361776515 hasConceptScore W2361776515C2993432071 @default.
- W2361776515 hasConceptScore W2361776515C71924100 @default.
- W2361776515 hasConceptScore W2361776515C95190672 @default.
- W2361776515 hasConceptScore W2361776515C98274493 @default.
- W2361776515 hasLocation W23617765151 @default.
- W2361776515 hasOpenAccess W2361776515 @default.
- W2361776515 hasPrimaryLocation W23617765151 @default.
- W2361776515 hasRelatedWork W2275034263 @default.
- W2361776515 hasRelatedWork W2348341135 @default.
- W2361776515 hasRelatedWork W2356831261 @default.
- W2361776515 hasRelatedWork W2359790819 @default.
- W2361776515 hasRelatedWork W2369232533 @default.
- W2361776515 hasRelatedWork W2369993338 @default.
- W2361776515 hasRelatedWork W2380483306 @default.
- W2361776515 hasRelatedWork W2387303160 @default.
- W2361776515 hasRelatedWork W2390623684 @default.
- W2361776515 hasRelatedWork W2393609978 @default.
- W2361776515 hasRelatedWork W2921128428 @default.
- W2361776515 hasRelatedWork W2972401485 @default.
- W2361776515 hasRelatedWork W2985194372 @default.
- W2361776515 hasRelatedWork W3029602810 @default.
- W2361776515 hasRelatedWork W3029759821 @default.
- W2361776515 hasRelatedWork W3031791656 @default.
- W2361776515 hasRelatedWork W3044155406 @default.
- W2361776515 hasRelatedWork W3083867742 @default.
- W2361776515 hasRelatedWork W3093243982 @default.
- W2361776515 hasRelatedWork W3154215952 @default.
- W2361776515 isParatext "false" @default.
- W2361776515 isRetracted "false" @default.
- W2361776515 magId "2361776515" @default.
- W2361776515 workType "article" @default.