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- W2361784766 abstract "Objective:To evaluate the efficacy of silibinin capsules for patients with chronic hep- atitis B (CHB). Methods: Sixty-eight patients with chronic hepatitis (abnormal ALT level) were equally randomized to receive either silibinin capsules (360mg) plus inosine (1200mg) daily or inosine monotherapy (1200mg) daily for 12 weeks. The primary endpoints were to monitor the improvement of abnormal ALT and AST in weeks 4,8 and 12 after the administration of the study drugs. Results:79.4 percent of patients treated with silibinin plus inosine experienced an ALT and AST normalization, compared to 32.3 percent of patients treated with inosine alone (P0.05). No serious adverse events were reported in the bicombination group in the course of the therapy. Conclusion: Addition of silibinin capsules to inosine regimen achieves a significant normalizatoin of the ALT and AST levels in patients with CHB." @default.
- W2361784766 created "2016-06-24" @default.
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- W2361784766 date "2005-01-01" @default.
- W2361784766 modified "2023-09-26" @default.
- W2361784766 title "Treatment of chronic hepatitis B with silibinin capsules" @default.
- W2361784766 hasPublicationYear "2005" @default.
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