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- W2361789510 abstract "Objective:Ventilator associated pneumonia(VAP) is a common nosocomial infection and is responsible for a very high mortality in neonatal intensive care unit(NICU) patients.This study was designed to investigate the changes in inflammatory mediators in plasma in ventilator associated pneumonia.Methods: A total of 252 children treated with ventilator support in our neonatal intensive care unit from 2003 to 2009.They were assigned and divided into two groups.The experimental group(162 children of them were without ventilator associated pneumonia) was the patients with VAP and the control group(90 children of them were diagnosed as ventilator associated pneumonia) was the patients without VAP.The contents of tumor necrosis factor-α(TNF-α),interleukin-6 in plasma were measured.Results: The detection rate of gram negative bacilli(76.7%) was the highest in VAP patients.There were statistical differences in the amount of inflammatory mediators released between the experimental group and the control group.In the experimental group,the contents of tumor necrosis factor-α(TNF-α),interleukin-6 in plasma increased obviously,but decreased after receiving effective treatment.Conclusions: Opportunistic drug resistant bacteria are common pathogens for VAP.Inflammatory mediators into plasma can be a indification for the occurrence and development of VAP." @default.
- W2361789510 created "2016-06-24" @default.
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- W2361789510 date "2010-01-01" @default.
- W2361789510 modified "2023-09-24" @default.
- W2361789510 title "Etiology and the Level of Inflammatory Mediators into Plasma in Ventilator Associated Pneumonia of Neonte" @default.
- W2361789510 hasPublicationYear "2010" @default.
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