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- W2361804413 abstract "Objective To evaluate the diagnostic efficiency of diffusion weighted imaging(DWI) with different b values,and to investigate the best cutoff value for differentiating benign from malignant lesions.Materials and Methods 155 cases with breast lesions underwent MR examinations.136 focal masses with b value of 0 and 500 s/mm2,and 122 with value of 0 and b 1000 s/mm2 by single-shot EPI sequence were performed.The average apparent diffusion coefficient(ADC),sensitivity,specificity and cutoff ADC value of DWI to distinguish malignant lesions were calculated seprately.Results The average ADC value of malignant lesions was lower than benign lesions,moreover the average ADC value was decreased with increased b value.The ROC curves were generated in order to determine the ADC thresholds that could balance the needs of sensitivity and specificity.We selected the ADC cutoff value of 1.11 × 10-3 mm2 /s mm2 /s for b = 1000 s/mm2 and 1.57 × 10-3 mm2 /s mm2 /s for b = 500 s/mm2.At the cutoff values,the sensitivity and specificity were 73.6% and 80.0% for b = 1000 s/mm2 and 83.3% and 56.9% for b = 500 s/mm2.Conclusion DWI with high bvalue has better spcificity than with low b value and can supplement DCE imaging findings to improve the accuracy of diagnosis." @default.
- W2361804413 created "2016-06-24" @default.
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- W2361804413 date "2010-01-01" @default.
- W2361804413 modified "2023-09-24" @default.
- W2361804413 title "The Study of DWI in Diagnosis of Breast Lesions with Differernt Bvalues" @default.
- W2361804413 hasPublicationYear "2010" @default.
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