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- W2361825146 abstract "OBJECTIVE To discuss the effect of cefoperazone/sulbactam combined with minocyline on treatment of Acinetobacter baumannii infections so as to guide the reasonable clinical use of antibiotics.METHODS The clinical data of 124cases of Acinetobacter baumannii infections treated by cefoperazone/sulbactam joint with minocyline were retrospective analyzed,and the conditions of drug sensitive test,clinical curative effect and minocyline adverse reaction.RESULTS The sensitivities of A.baumannii against cefoperazone/sulbactam high were notable higher than the other antimicrobial agents.The resistance of A.baumannii was high to ampicillin,ammonia QuNa,nitrofurantoin,cefazolin,and the drug resistance rates were 100%.The total effective rate was 72.6%,and the bacteria clearance rate was 35.5%.There were 14cases of patients with such adverse reactions as mild nausea and abdominal distension,which were relieved after drug treatment.CONCLUSIONAccording to the drug susceptibility testing,the cefoperazone/sulbactam combined with minocyline can achieve good effect on the treatment of the patients with A.baumannii infections,with the adverse reactions less,and safety high." @default.
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- W2361825146 date "2013-01-01" @default.
- W2361825146 modified "2023-09-24" @default.
- W2361825146 title "Effect of cefoperazone/sulbactam combined with minocyline on treatment of Acinetobacter baumannii infection" @default.
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