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- W2361848242 abstract "【Objective】 To research on the safety of PAMAM-D(polyamidoamine dendrimers) mediated foreign gene transfection into pig sperm cells for xenotransplantation.【Methods】 PAMAM-D/hDAF cDNA compounds were made.Then PAMAM-D and the compounds were incubated with washed pig sperm cells.Next,the effects on sperm motility and deformity were evaluated through Sperm Quality Inspection Workstation in the different groups.【Results】 PAMAM-D and the compounds had no obvious impact on sperm motility and deformity through evaluation in Sperm Quality Inspection Workstation.【Conclusion】 As a vector,PAMAM-D and PAMAM-D/hDAF cDNA compounds have no cytotoxicity on pig sperm cells.The approach may provide a safe method for the production of transgenic pigs for xenotransplantation." @default.
- W2361848242 created "2016-06-24" @default.
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- W2361848242 date "2011-01-01" @default.
- W2361848242 modified "2023-09-23" @default.
- W2361848242 title "Research on safety of polyamidoamine dendrimers mediated foreign gene transfection into pig sperm cells for xenotransplantation" @default.
- W2361848242 hasPublicationYear "2011" @default.
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