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- W2361883851 abstract "Objective:To explore the effect of Fluoxetine plus conjugated estrogen on treatment of menopausal depression.Methods:106 menopausal women with depression were randomly divided into three groups: 39 cases in combining group were treated with Fluoxetine and conjugated estrogen once a day,respectively.36 cases in Fluoxetine only group received one tablet for one day.And 31 cases in HRT only group took conjugated estrogen once a day.The total regimen was 8 weeks.The degree of melancholia and improvement of menopausal symptoms were assessed by HAMD and Kupperman measurement index(KMI),respectively.Results:The score of HAMD in combining group,Fluoxetine group,and HRT group was 23.01±3.54,23.02±4.38,23.04±4.56 before treatment,and decreased to 4.98±4.48,6.97±5.44 and 10.01± 5.75,respectively.The difference was statistically significance(P0.001);The HAMD score in combining group had more decrease than thau in HRT group(P0.01).The KMI score was 32.10±7.42,31.83±7.65 and 32.01±7.29 in three groups before treatment and 7.57±4.64, 16.09±6.06,and 9.70±7.02 after treatment,respectively(P0.001);KMI score decrement in combining group and HRT group was higher than that in Fluoxetine group(P0.01).Conclusion:The regimen of Fluoxetine plus conjugated estrogen can enhance the curative effect in treatment of menopausal women with depression." @default.
- W2361883851 created "2016-06-24" @default.
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- W2361883851 date "2006-01-01" @default.
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- W2361883851 title "Comparison of three regimens for treatment of menopausal women with depression" @default.
- W2361883851 hasPublicationYear "2006" @default.
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