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- W2361899822 abstract "Objective To investigate the effects of ramipril on the numbers of circulating endothelial cells(CEC),plasma brain natriuretic peptide(BNP),endothelin-1(ET-1)and6-keto-prostaglandin F 1α (6-Keto-PGF 1α )levˉ els in patients with congestive heart failure(CHF).Methods CEC counting,plasma BNP,ET-1and6-Keˉto-PGF 1α concentrations were detected before and after two weeks of oral treatment with ramipril in25patients with CHF.Results The numbers of CEC,the contents of plasma BNP and ET-1were significantly increased and content of6-Keto-PGF 1α was markedly decreased in patients with CHF(P0.01).A significant decreased CEC counting,plasma BNP and ET-1contents and increased6-Keto-PGF 1α level were observed after two weeks of ramipril therapy(P0.01).Conclusions The structure and function of vascular endothelial cells are damaged in patients with CHF and ramipril has a beneficial effect on vascular endothelial cells." @default.
- W2361899822 created "2016-06-24" @default.
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- W2361899822 date "2004-01-01" @default.
- W2361899822 modified "2023-09-23" @default.
- W2361899822 title "Effects of Ramipril on Circulating Endothelial Cells and Plasma Brain Natriuretic Peptide in Patients with Congestive Heart Failure" @default.
- W2361899822 hasPublicationYear "2004" @default.
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