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- W2361917416 abstract "Objective: To explore the efficacy of valproate sodium on the aggressive behavior of the patients with schizophrenia.Methods: A total of 60 inpatients with schizophrenia were randomly assigned to two groups: the study group and the controlled group,and the former was treated with risperidone combined with valproate sodium,while the latter with risperidone alone. The positive and negative syndrome scale( PANSS),Modified Overt Aggression Scales( MOAS) were comparable for the two groups prior to the therapy and in weeks 1,2,4,8. Results: The PANSS and MOAS total scores of the two groups were all significantly lower than prior to the therapy at the at the endpoint of weeks 1,2,4,8( P 0. 01 or P 0. 05). The PANSS and MOAS scores of the study group were significantly lower than the controlled group at the endpoint of weeks 2,4,8( P 0. 01). There were no significance in the incidence rate of adverse events in the two groups( P 0. 05). Conclusion: The risperidone with valproate sodium can be more effective in treatment of schizhophrenia than the risperidone alone,also can control the aggressive behavior more effectively." @default.
- W2361917416 created "2016-06-24" @default.
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- W2361917416 date "2014-01-01" @default.
- W2361917416 modified "2023-09-26" @default.
- W2361917416 title "The comparative study of the efficacy of risperidone combined with valproate sodium on the aggressive behavior of the patients with schizophrenia" @default.
- W2361917416 hasPublicationYear "2014" @default.
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