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- W2361922729 abstract "Objective To explore the mechanism of early-onset sub-clinical seizures following acute cerebral infarction. Methods Right middle cerebral artery occlusion (MCAO) rats models were made by threads methods. Sub-clinical seizures were detected with recording apparatus at the same time. Glial glutamate transporter-1 (GLT-1) were detected by immunohistochemical method in rats hippocampus. Results Sub-clinical seizures occurred in 27.4% rats following MCAO. The GLT-1 expressions in CA_1 and CA_3 regions were lower in sub-clinical seizure group[(344.5±35.0)μm~2 and (360.4±13.5)μm~2 respectively] than those in the controls[(447.0±22.8)μm~2 in CA_1 region and (402.3±28.5)μm~2 in CA_3 region]. But there were not significant differences of GLT-1 immunoreactivities in dentate gyrus between the two groups above. Conclusion Early-onset sub-clinical seizures occur following the acute MCAO in rats, which should be related to the decreased expression of GLT-1 in CA_1 and CA_3 of hippocampus." @default.
- W2361922729 created "2016-06-24" @default.
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- W2361922729 date "2005-01-01" @default.
- W2361922729 modified "2023-09-24" @default.
- W2361922729 title "Expression of GLT-1 in rats hippocampus of early-onset sub-clinical seizures following acute cerebral infarction" @default.
- W2361922729 hasPublicationYear "2005" @default.
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