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- W2361935900 abstract "Objective To study the association among HIF-1α,HIF-2α,VEGF,and bone metabolism in senior male with primary osteoporosis in Qinghai-Tibetan high plateau. Me thods Sixty osteoporosis patients and 58 normal people were enrolled.Serum HIF-1α,HIF-2α,VEGF,BGP,and TRACP-5b were measured using ELISA method. BMD of the 3 regions was assessed with Durex GE image system. Re sults BGP and BMD of the 3 regions decreased significantly in OP group comparing to those in control group. TRCAP-5b as well as serum HIF-1α and VEGF increased. The correlation study indicated that HIF-1α were positively correlated with VEGF and BGP,but negatively related with BMD and TRACP-5b in OP group( P 0. 05). VEGF was positively correlated with BMD( P 0. 05). Conclusion Patients with osteoporosis in high plateau region should pay attention to have oxygen supplement,in order to reduce damage due to hypoxia. They also need to have calcium supplement and more exercise,in order to prevent from osteoporosis." @default.
- W2361935900 created "2016-06-24" @default.
- W2361935900 creator A5066578826 @default.
- W2361935900 date "2015-01-01" @default.
- W2361935900 modified "2023-09-23" @default.
- W2361935900 title "The correlation among serum hypoxia-inducible factor-1α,hypoxia-inducible factor 2α,vascular endothelial growth factor,and bone mineral density and bone metabolism in senior men with osteoporosis in Qinghai-Tibetan high plateau" @default.
- W2361935900 hasPublicationYear "2015" @default.
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