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- W2361960113 abstract "Objective: To investigate the relationship between IgG subclass against Helicobacter pylori (HP) infection and gastroduodenal diseases in Chinese patients. Methods: Serum samples were obtained from 129 patients with peptic ulcer or gastritis in Shanghai(n=55) and Guangxi(n=74). IgG subclass against Hp in patients infected with Hp were detected by ELISA and the relationship between IgG subclass responses and gastroduodenal diseases was assessed. Results: The major IgG subclasses to the whole cell antigen were IgG1 and IgG2, and the levels of IgG3 and IgG4 were very low. The level of IgG2 subclass in patients with duodenal ulcer was higher than that in patients with non ulcer dyspepsia. The levels of IgG1, IgG3 and IgG4 were not significantly different between duodenal ulcer and non-ulcer dyspepsia. Conclusion: Hp IgG2 may be a good indicator for peptic ulcer." @default.
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- W2361960113 date "2004-06-15" @default.
- W2361960113 modified "2023-10-17" @default.
- W2361960113 title "Changes of IgG Subclass against Helicobacter pylori in Chinese Patients with HP Infection" @default.
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