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- W2361961330 abstract "Objective: To discuss the clinical value of the change of brain natriuretic peptide(BNP) in children with Kawasaki disease(KD).Methods: 36 cases of patients with KD were enrolled in KD group,the level of plasma BNP was detected in acute phase and recovery phase.36 cases of patients with acute upper respiratory infection were enrolled in control group,the level of plasma BNP was detected.White blood cell count,C-reactive protein and serum cardiac troponin I were measured in two groups.Echocardiogram was used to detected the pathological change of coronary artery in KD group.Results: In acute phase of KD group,the level of plasma BNP was(468.4±200.6) ng/L,which was higher than that of recovery phase and control group [(91.5±12.7) ng/L,(72.3±13.5) ng/L],the difference was statistically significant(all P0.01).10 cases of coronary artery change were found through echocardiogram detected in acute phase of KD group,compared with patients without coronary artery change in KD group,the BNP level had no significant difference(P0.05).In acute phase of KD group,BNP level correlated positively with C-reactive protein,white blood cells counts and serum cTnI(r=0.605,0.532,0.591,all P0.05).Conclusion: In KD group,the level of plasma BNP increases in acute phase and decreases significantly in recovery phase,which is conductive to diagnose of acute phase of KD.The correlation between the plasma BNP level in acute phases of KD with the damage of heart and coronary artery still need further study." @default.
- W2361961330 created "2016-06-24" @default.
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- W2361961330 date "2011-01-01" @default.
- W2361961330 modified "2023-09-27" @default.
- W2361961330 title "Clinical value of the change of brain natriuretic peptide in children with Kawasaki disease" @default.
- W2361961330 hasPublicationYear "2011" @default.
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