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- W2362012380 abstract "Objective To investigate the impact of different type and severity of hypertension on diabetic retinopathy, nephropathy and abnormal ECG. Methods 5841 patients from the diabetic complication assessment database from 1994 to 2006 were divided into the eight groups: group A (GA,n=3580, BP140/90 mmHg), group B (GB,n=456, BP140/90 mmHg, with hypotensive agents), group C (GC,n=1271, BP=140-159/90-99 mmHg), group D (GD,n=396, BP=160-179/100-109 mmHg), group E (GE,n=138, BP≥180 /110 mmHg), group 3 (G3,n=1262, systolic hypertension only), group 4 (G4,n=103, diastolic hypertension only) and group 5 (G5,n=440, both systolic and diastolic hypertension). Results Of these patients, 1006 patients had retinopathy, including 898 (15.37%) with background retinopathy and 108 (1.85 %) with proliferative retinopathy; 1145 had elevated urine albumin excretion, 1077 had abnormal ECG. The prevalences of retinopathy, nephropathy and the abnormal ECG were increased from 15.0%, 17.2%, 29.9% in group A to 34.8 %, 54.5 %, 66.7% in group E.No differences in the prevalence of retinopathy and nephropathy between group A and group B (15.0 % vs.17.8 %; 17.2 % vs.16.3 % respectively).There were significant differences in the ECG abnormalities between different groups (29.9 % for group A, 37.4% for group B, 40.5% for group C, 49.4 % for group D and 66.7 % for group E). There were significant differences in the prevalence of retinopathy, nephropathy and ECG abnormalities among group 3 (21.6 %, 46.7 %, 42.3 %), group 4 (11.0%, 35.6%, 45.0%), and group 5 (22.8%, 47.3%, 49.5%) respectively. Conclusions Hypertension aggravates retinopathy, nephropathy and ECG abnormalities in the diabetic patients.Reasonably controlled blood pressure significantly decreases the prevalence of diabetic retinopathy, albuminuria and ECG abnormalities." @default.
- W2362012380 created "2016-06-24" @default.
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- W2362012380 date "2008-01-01" @default.
- W2362012380 modified "2023-09-26" @default.
- W2362012380 title "The impact of different type and severity of hypertension on retinopathy, nephropathy and the ECG abnormalities in diabetic patients" @default.
- W2362012380 hasPublicationYear "2008" @default.
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