Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362028131> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2362028131 abstract "Objective To investigate the effects and mechanisms of lactic acid bacteria on MAPK signaling in immune response of dust mite sensitized mice.Methods Forty C57BL/6 mice in Group M,P and L, were sensitized and challenged with mite extract while then the animals in Group N were treated with saline as control.The mice in Group L and P were fed with Lactococcus lactis or Lactobacillus respectively.Three days after the last challenge,all mice were sacrificed for lung pathological examination.IL-10 level in culture supernatant of splenocytes stimulated with mite extract was detected by ELISA.The expression of IL-4/IFN-γ on CD3+CD4+ cells was detected by flow cytometry.Western blot were performed for detection of MAPK signaling(P38,ERK,and JNK) from mice' s spleen cells stimulated with mite extract.Results The mice fed with Lactococcus lactis(Group L) had lower rate of eosinophilic airway inflammation and higher level of IL-10 in the culture supernatant of splenocytes than Group P.Meanwhile,the number of CD4+ T cell with IL-4 expression was decreased revealed by the analysis of flow cytometry.P38 signaling in spleen cells was activated in the mice of Group M,similarly in the mice of Group P,but not of Group L.Conclusion Oral treatment of Lactococcus lactis can induce an immune tolerance in response to mite by up-regulating the level of Tr cells secreting IL-10,thus inhibiting activation of P38 signaling." @default.
- W2362028131 created "2016-06-24" @default.
- W2362028131 creator A5046328933 @default.
- W2362028131 date "2011-01-01" @default.
- W2362028131 modified "2023-09-23" @default.
- W2362028131 title "Effects of Lactic Acid Bacteria on Dust Mite Induced Allergic Inflammation in Mice Involving the Regulation of MAPK Signaling" @default.
- W2362028131 hasPublicationYear "2011" @default.
- W2362028131 type Work @default.
- W2362028131 sameAs 2362028131 @default.
- W2362028131 citedByCount "0" @default.
- W2362028131 crossrefType "journal-article" @default.
- W2362028131 hasAuthorship W2362028131A5046328933 @default.
- W2362028131 hasConcept C141105273 @default.
- W2362028131 hasConcept C153911025 @default.
- W2362028131 hasConcept C159654299 @default.
- W2362028131 hasConcept C189976730 @default.
- W2362028131 hasConcept C203014093 @default.
- W2362028131 hasConcept C2775920511 @default.
- W2362028131 hasConcept C2776914184 @default.
- W2362028131 hasConcept C2778166374 @default.
- W2362028131 hasConcept C2780011460 @default.
- W2362028131 hasConcept C2780931953 @default.
- W2362028131 hasConcept C523546767 @default.
- W2362028131 hasConcept C54355233 @default.
- W2362028131 hasConcept C553184892 @default.
- W2362028131 hasConcept C55493867 @default.
- W2362028131 hasConcept C57074206 @default.
- W2362028131 hasConcept C62478195 @default.
- W2362028131 hasConcept C71924100 @default.
- W2362028131 hasConcept C86803240 @default.
- W2362028131 hasConcept C8891405 @default.
- W2362028131 hasConcept C89423630 @default.
- W2362028131 hasConceptScore W2362028131C141105273 @default.
- W2362028131 hasConceptScore W2362028131C153911025 @default.
- W2362028131 hasConceptScore W2362028131C159654299 @default.
- W2362028131 hasConceptScore W2362028131C189976730 @default.
- W2362028131 hasConceptScore W2362028131C203014093 @default.
- W2362028131 hasConceptScore W2362028131C2775920511 @default.
- W2362028131 hasConceptScore W2362028131C2776914184 @default.
- W2362028131 hasConceptScore W2362028131C2778166374 @default.
- W2362028131 hasConceptScore W2362028131C2780011460 @default.
- W2362028131 hasConceptScore W2362028131C2780931953 @default.
- W2362028131 hasConceptScore W2362028131C523546767 @default.
- W2362028131 hasConceptScore W2362028131C54355233 @default.
- W2362028131 hasConceptScore W2362028131C553184892 @default.
- W2362028131 hasConceptScore W2362028131C55493867 @default.
- W2362028131 hasConceptScore W2362028131C57074206 @default.
- W2362028131 hasConceptScore W2362028131C62478195 @default.
- W2362028131 hasConceptScore W2362028131C71924100 @default.
- W2362028131 hasConceptScore W2362028131C86803240 @default.
- W2362028131 hasConceptScore W2362028131C8891405 @default.
- W2362028131 hasConceptScore W2362028131C89423630 @default.
- W2362028131 hasLocation W23620281311 @default.
- W2362028131 hasOpenAccess W2362028131 @default.
- W2362028131 hasPrimaryLocation W23620281311 @default.
- W2362028131 hasRelatedWork W1969506811 @default.
- W2362028131 hasRelatedWork W2006262980 @default.
- W2362028131 hasRelatedWork W2013660949 @default.
- W2362028131 hasRelatedWork W2048623067 @default.
- W2362028131 hasRelatedWork W2068182622 @default.
- W2362028131 hasRelatedWork W2084254906 @default.
- W2362028131 hasRelatedWork W2143294640 @default.
- W2362028131 hasRelatedWork W2289222174 @default.
- W2362028131 hasRelatedWork W2341453888 @default.
- W2362028131 hasRelatedWork W2381426847 @default.
- W2362028131 hasRelatedWork W2409595657 @default.
- W2362028131 hasRelatedWork W2436021668 @default.
- W2362028131 hasRelatedWork W2442682190 @default.
- W2362028131 hasRelatedWork W3010836190 @default.
- W2362028131 hasRelatedWork W3044309271 @default.
- W2362028131 hasRelatedWork W3146015330 @default.
- W2362028131 hasRelatedWork W3210613443 @default.
- W2362028131 hasRelatedWork W59419184 @default.
- W2362028131 hasRelatedWork W2289997464 @default.
- W2362028131 hasRelatedWork W2939219296 @default.
- W2362028131 isParatext "false" @default.
- W2362028131 isRetracted "false" @default.
- W2362028131 magId "2362028131" @default.
- W2362028131 workType "article" @default.