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- W2362029305 abstract "Objective To study the effect of intensive lipid-lowering by simvastatin on the aged coronary heart disease.Methods 120 patients with the aged coronary heart disease were randomized to receive either intensive lipid-lowering(60 cases by simvastatin 40 mg) or conventional treatment(60 cases by simvastatin 20mg).After 1-month,3-month,6-month and 12-month theatment,the levels of TC,TG,LDL-C and hs-CRP were determined.The observation projects also included the attainment rates and the incident rates of cardic event.Results The levels of TC,TG,LDL-C and hs-CRP decreased significantly in both group(P0.01).More significant decrease in patients of intensive lipid-lowering group was found than those in the control group(P0.05).The attainment rates of lipid were higher in intensive lipid-lowering group than that in control group after 6 months for treatment(31% vs 8 %,P0.01).The incident rates of cardic event were lower in intensive lipid-lowering group than that in control group(14% vs 33%,P0.05).Conclusions Intensive lipid-lowering by simvastatin could decrease the levels of plasma of TC,TG,LDL-C and hs-CRP,improve the blood supply of cardiac muscle,and inbibit the process of coronary heart disease." @default.
- W2362029305 created "2016-06-24" @default.
- W2362029305 creator A5032447166 @default.
- W2362029305 date "2009-01-01" @default.
- W2362029305 modified "2023-09-23" @default.
- W2362029305 title "Effect of intensive lipid-lowering by simvastatin on the aged coronary heart disease" @default.
- W2362029305 hasPublicationYear "2009" @default.
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