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- W2362046845 abstract "Bombyx mori cytoplasmic polyhedrovirus(BmCPV) infects epithelial cells of silkworm larval midgut,leading to midgut polyhedrosis. Understanding the mechanism of BmCPV infection can contribute to formulate scientific prevention strategies. As an immune mechanism,autophagy plays important role in the resistance of microorganisms. The expressional variation of autophagy-related gene 8( ATG8) protein in silkworm larval midgut of the 4th instar was assayed using immunohistochemical method. The results showed that the expressional level of ATG8 protein in midgut was significantly higher than the normal level at 1 h to 8 h after the silkworm larvae were infected by BmCPV,but decreased to background level at 8 h to 35 h post infection. Then the expressional level of ATG8 protein increased sharply again at 51 h and achieved a peak at 99 h. At 62 h post infection,viral polyhedra emerged in the columnar cells of midgut epithelial layer. These results suggest that there is certain relationship between autophagy response and BmCPV infection in silkworm larvae." @default.
- W2362046845 created "2016-06-24" @default.
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- W2362046845 date "2014-01-01" @default.
- W2362046845 modified "2023-09-25" @default.
- W2362046845 title "Expressional Variation of Autophagy-related Protein ATG8 in the Midgut of Silkworm( Bombyx mori) During BmCPV Infection" @default.
- W2362046845 hasPublicationYear "2014" @default.
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