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- W2362064473 abstract "Purpose To assess the efficacy of IgH gene rearrangement analysis in the fine needle aspiration of lymph tissue as an adjunct to cytologic diagnosis.Methods One hundred and fifty-nine cases of lymphoid tissues obtained by fine needle aspiration were collected and IgH gene rearrangements detected by PCR were examined.The results of gene rearrangements were compared with diagnoses from subsequent surgical biopsies.Results The positive rate of IgH gene rearrangement detection was 72.22% in B-NHL and zero in 4 cases of T-NHL.In 102 cases of reactive lymphnodes aspiration,only 4 had monoclonality result.The specificity was 96.08%.Conclusions For fine needle aspiration of lymph node,determination of clonality through IgH gene rearrangement analysis is a useful diagnostic assay.But this assay is not efficient in the differentiation between Lymphoma and other metastatic malignant tumors." @default.
- W2362064473 created "2016-06-24" @default.
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- W2362064473 date "2008-01-01" @default.
- W2362064473 modified "2023-09-23" @default.
- W2362064473 title "Value of IgH gene rearrangement analysis using PCR in assistant diagnosis of lymphoproliferative disorders by fine needle aspiration" @default.
- W2362064473 hasPublicationYear "2008" @default.
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