Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362077039> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2362077039 abstract "Objective To study the anti-androgen effect of cadmium chloride. Methods Forty adult male castrated Sprague-Dawley rats were randomly divided into negative control group,0. 080,0. 200,2. 000 mg·kg- 1cadmium chloride + testosterone propionate( TP) group and flutamide + TP group,with eight rats in each group. All rats were administrated with TP( 0. 4 mg·kg- 1) once daily for 10 days. Based on this,negative control group was administrated peanut oil with a dose of 10 mL·kg- 1by intraperitoneal injection. The different doses of cadmium chloride + TP group were administrated 0. 080, 0. 200,2. 000 mg·kg- 1cadmium chloride by intraperitoneal injection respectively. The injection volume was 10 mL·kg- 1. Flutamide + TP group was administrated flutamide by intragastric administration with the dose of 50 mg·kg- 1. The blood was collected via the femoral artery at 24 hours after the last administration and then the animals were sacrificed. The weight of androgen dependent organs was measured and the organ coefficient was calculated. The levels of serum testosterone were detected by radioimmunoassay. Results Compared with the negative control group,the growth of body weight of 2. 000 mg·kg- 1cadmium chloride + TP group was significantly lower( P 0. 05),and the organ coefficients of androgen dependent organs and levels of serum testosterone were decreased significantly in flutamide + TP group( P 0. 05). Conclusion Cadmium may have not the anti-androgen activity in this assay protocol." @default.
- W2362077039 created "2016-06-24" @default.
- W2362077039 creator A5030998593 @default.
- W2362077039 date "2014-01-01" @default.
- W2362077039 modified "2023-09-25" @default.
- W2362077039 title "Anti-androgenic activity of cadmium chloride in hershberger assays" @default.
- W2362077039 hasPublicationYear "2014" @default.
- W2362077039 type Work @default.
- W2362077039 sameAs 2362077039 @default.
- W2362077039 citedByCount "0" @default.
- W2362077039 crossrefType "journal-article" @default.
- W2362077039 hasAuthorship W2362077039A5030998593 @default.
- W2362077039 hasConcept C121608353 @default.
- W2362077039 hasConcept C126322002 @default.
- W2362077039 hasConcept C134018914 @default.
- W2362077039 hasConcept C176685330 @default.
- W2362077039 hasConcept C178790620 @default.
- W2362077039 hasConcept C185592680 @default.
- W2362077039 hasConcept C2777911890 @default.
- W2362077039 hasConcept C2778313021 @default.
- W2362077039 hasConcept C2778643788 @default.
- W2362077039 hasConcept C2779279991 @default.
- W2362077039 hasConcept C2780159080 @default.
- W2362077039 hasConcept C2780192828 @default.
- W2362077039 hasConcept C2781115071 @default.
- W2362077039 hasConcept C544657597 @default.
- W2362077039 hasConcept C61367390 @default.
- W2362077039 hasConcept C71315377 @default.
- W2362077039 hasConcept C71924100 @default.
- W2362077039 hasConceptScore W2362077039C121608353 @default.
- W2362077039 hasConceptScore W2362077039C126322002 @default.
- W2362077039 hasConceptScore W2362077039C134018914 @default.
- W2362077039 hasConceptScore W2362077039C176685330 @default.
- W2362077039 hasConceptScore W2362077039C178790620 @default.
- W2362077039 hasConceptScore W2362077039C185592680 @default.
- W2362077039 hasConceptScore W2362077039C2777911890 @default.
- W2362077039 hasConceptScore W2362077039C2778313021 @default.
- W2362077039 hasConceptScore W2362077039C2778643788 @default.
- W2362077039 hasConceptScore W2362077039C2779279991 @default.
- W2362077039 hasConceptScore W2362077039C2780159080 @default.
- W2362077039 hasConceptScore W2362077039C2780192828 @default.
- W2362077039 hasConceptScore W2362077039C2781115071 @default.
- W2362077039 hasConceptScore W2362077039C544657597 @default.
- W2362077039 hasConceptScore W2362077039C61367390 @default.
- W2362077039 hasConceptScore W2362077039C71315377 @default.
- W2362077039 hasConceptScore W2362077039C71924100 @default.
- W2362077039 hasLocation W23620770391 @default.
- W2362077039 hasOpenAccess W2362077039 @default.
- W2362077039 hasPrimaryLocation W23620770391 @default.
- W2362077039 hasRelatedWork W2039391269 @default.
- W2362077039 hasRelatedWork W2136460167 @default.
- W2362077039 hasRelatedWork W2171420235 @default.
- W2362077039 hasRelatedWork W2181709408 @default.
- W2362077039 hasRelatedWork W2352451238 @default.
- W2362077039 hasRelatedWork W2367948508 @default.
- W2362077039 hasRelatedWork W2369685727 @default.
- W2362077039 hasRelatedWork W2370473366 @default.
- W2362077039 hasRelatedWork W2372974242 @default.
- W2362077039 hasRelatedWork W2380426620 @default.
- W2362077039 hasRelatedWork W2381973145 @default.
- W2362077039 hasRelatedWork W2391779804 @default.
- W2362077039 hasRelatedWork W2392476889 @default.
- W2362077039 hasRelatedWork W2474140707 @default.
- W2362077039 hasRelatedWork W2600783572 @default.
- W2362077039 hasRelatedWork W2620250245 @default.
- W2362077039 hasRelatedWork W2967573340 @default.
- W2362077039 hasRelatedWork W3025348430 @default.
- W2362077039 hasRelatedWork W3029444144 @default.
- W2362077039 hasRelatedWork W2183367468 @default.
- W2362077039 isParatext "false" @default.
- W2362077039 isRetracted "false" @default.
- W2362077039 magId "2362077039" @default.
- W2362077039 workType "article" @default.