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- W2362085842 abstract "OBJECTIVE: To study the expressions of vascular endothelial growth factor C, D (VEGF-C, VEGF-D)and lymphatic micro-vessel density (lymphatic microvessel density,LMVD)in colorectal carcinoma and their relation to the clinicopathological parameters. METHODS: The expressions of vascular endothelial growth factor C, D were studied by using SP immunohistochemical staining and 5′-nucleotidase-enzyme-histochemical staining for lymphatic microvessel in 50 specimens of colorectal carcinomas tissue and colorectal normal tissue. RESULTS: LMVD was correlated with the expressions of VEGF-C and -D. The VEGF-C and -D expressions and LMVD were correlated with lymphatic metastasis and Duke stage. CONCLUSION: VEGF-C,VEGF-D/VEGFR-3 signaling pathway promots lymphangiogenesis, increases LMVD, drives lymphatic metastasis in colorectal carcinoma." @default.
- W2362085842 created "2016-06-24" @default.
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- W2362085842 date "2008-01-01" @default.
- W2362085842 modified "2023-09-25" @default.
- W2362085842 title "Significance of lymphangiogenesis and lymphatic metastasis in colorectal carcinoma" @default.
- W2362085842 hasPublicationYear "2008" @default.
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