Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362093440> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- W2362093440 abstract "Solid phase peptide synthesis(SPPS) is a process by which chemical transformations can be carried out on solid support in order to synthesize peptide and protein. This idea was first conceived by Bruce Merrifield in 1959 and achieved in 1963. Bruce Merrifield also he devised the first prototype of an automated peptide synthesizer by 1965. Using SPPS,Bruce Merrifield synthesize many kind of peptide,such as bradykinin,angiotensin,oxytocin and insulin,especially ribonuclease A (124 amino acids) in 1969. SPPS method has been also used widely for oligonucleotides and carbohydrates and is seen as one of the fundamental techniques of genetic and biochemical research. Merrifield was awarded the Nobel Prize in Chemistry 1984 for his development of methodology for chemical synthesis on a solid matrix. In this article,Both Merrifield life and SPPS invention process are introduced so as to understand Merrifield original contributions." @default.
- W2362093440 created "2016-06-24" @default.
- W2362093440 creator A5022473195 @default.
- W2362093440 date "2010-01-01" @default.
- W2362093440 modified "2023-09-25" @default.
- W2362093440 title "Inventor of Solid Phase Peptide Synthesis:Robert Bruce Merrifield" @default.
- W2362093440 hasPublicationYear "2010" @default.
- W2362093440 type Work @default.
- W2362093440 sameAs 2362093440 @default.
- W2362093440 citedByCount "0" @default.
- W2362093440 crossrefType "journal-article" @default.
- W2362093440 hasAuthorship W2362093440A5022473195 @default.
- W2362093440 hasConcept C129312508 @default.
- W2362093440 hasConcept C185592680 @default.
- W2362093440 hasConcept C21951064 @default.
- W2362093440 hasConcept C2776469878 @default.
- W2362093440 hasConcept C2779281246 @default.
- W2362093440 hasConcept C2779809887 @default.
- W2362093440 hasConcept C41008148 @default.
- W2362093440 hasConcept C552990157 @default.
- W2362093440 hasConcept C55493867 @default.
- W2362093440 hasConceptScore W2362093440C129312508 @default.
- W2362093440 hasConceptScore W2362093440C185592680 @default.
- W2362093440 hasConceptScore W2362093440C21951064 @default.
- W2362093440 hasConceptScore W2362093440C2776469878 @default.
- W2362093440 hasConceptScore W2362093440C2779281246 @default.
- W2362093440 hasConceptScore W2362093440C2779809887 @default.
- W2362093440 hasConceptScore W2362093440C41008148 @default.
- W2362093440 hasConceptScore W2362093440C552990157 @default.
- W2362093440 hasConceptScore W2362093440C55493867 @default.
- W2362093440 hasLocation W23620934401 @default.
- W2362093440 hasOpenAccess W2362093440 @default.
- W2362093440 hasPrimaryLocation W23620934401 @default.
- W2362093440 hasRelatedWork W1998522945 @default.
- W2362093440 hasRelatedWork W2024211374 @default.
- W2362093440 hasRelatedWork W2165795128 @default.
- W2362093440 hasRelatedWork W2202717481 @default.
- W2362093440 hasRelatedWork W2320784305 @default.
- W2362093440 hasRelatedWork W2333470577 @default.
- W2362093440 hasRelatedWork W2911855118 @default.
- W2362093440 hasRelatedWork W3026909863 @default.
- W2362093440 hasRelatedWork W348205287 @default.
- W2362093440 hasRelatedWork W1600532144 @default.
- W2362093440 hasRelatedWork W2814471952 @default.
- W2362093440 isParatext "false" @default.
- W2362093440 isRetracted "false" @default.
- W2362093440 magId "2362093440" @default.
- W2362093440 workType "article" @default.