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- W2362117478 abstract "Objective To determine the change of the level of the adenine nucleotides in liver tissue of systemic inflammatory response syndrome (SIRS) rats, the effect of mild hypothermia on SIRS rats was investigated. Methods 24 Wistar rats were divided randomly into normal control (NC,8) group, lipopolysaccharide (LPS,8) group , mild hypothermia theatment (MHT,8) group .The levels of Adenine nucleotides were determined by high performance liquid chromatography (HPLC) . Result Compared with the levels of adenine nucleotide in liver tissue of NC group rats (ATP 4.990±0.455, ADP 1.632±0.181 ,AMP 1.737±0.407μmol/g.wet), the levels of adenine nucleotides in liver tissue of LPS group rats(ATP 4.093±0.424,ADP 1.331±0.136 ,AMP 1.331±0.312μmol/g.wet)and MHT group rats(ATP 4.519±0.028,ADP 1.483±0.108,AMP 1.544±0.301μmol/g.wet)were decreased. The levels of adenine nucleotides increased significantly in MHT group rats than in LPS group rats. Conclusion Mild hypothermia could decrease the energy damage in the liver tissue of SIRS rats." @default.
- W2362117478 created "2016-06-24" @default.
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- W2362117478 date "2005-01-01" @default.
- W2362117478 modified "2023-09-25" @default.
- W2362117478 title "Experimental Study on the Effects of Mild Hypothermia on the Liver Tissue Energy of SIRS Rats" @default.
- W2362117478 hasPublicationYear "2005" @default.
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