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- W2362120798 abstract "Objective The effects of Brain Natriuretic Peptide on the function of rats arteriosclerosis model vascular endothelial.Methods 40 healthy wistar rats,divided into five groups at random,eight rats in contorl group,eight in model group,each of the treatment group of nitrates(Hua ren xin shu),Sodium Ferulate(Haisi)、rhBNP(xinhuosu) model group were eight rats.Adopt enzyme-linked immunosorbent adsorption(ELISA) methods to determine each rat treatment and serum blood TXB2 and 6-Keto-PGF1a content,and light-microscopy each rat before and after processing the aortic lining cells changes.Results a.The treatment group serum TXB2 and 6-Keto-PGF1a levels obviously different than before(P0.05).b.The treatment of each group in serum TXB2 and 6-Keto-PGF1a content is difference(P0.05).c.Optical microscope observations,the control group vascular lumen,no calcium sediment,big plaques can be seen.Smooth muscle cells is boom and ectoblast is conjunction tissue,arranging disorganized.The treatment group is smoother,local macrophage adhesion,visible EC missing,but better than model group,and the treatment group showed no significant difference between.Conclusion rhBNP can not only increases the content of PGI2 arterial stiffness rat models,lower TXA2 level,but also atherosclerosis rats damage,vascular endothelial protecting endothelial function." @default.
- W2362120798 created "2016-06-24" @default.
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- W2362120798 date "2013-01-01" @default.
- W2362120798 modified "2023-09-24" @default.
- W2362120798 title "The effects of Brain Natriuretic Peptide on the function of rats arteriosclerosis model vascular endothelial" @default.
- W2362120798 hasPublicationYear "2013" @default.
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