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- W2362173840 abstract "Objective:To evaluate the expression of μ opioid receptor of the knee joint synovium tissue in patients with chronic inflammation.Methods:The patients were divided into an inflammatory group and a control group.Those who were allocated to the inflammatory group(n=25) were diagnosed as osteoarthritis by arthroscopy.In the control group(n=25),the patients were having dislocation of patella and took internal fixation with arthroscopy.μ opioid receptor in the synovium was measure by immunohistochemistry and RT-PCR in both groups.Results:Immunohistochemical and RT-PCR results revealed that the expression of mRNA and the optical density(OD) of immunoreaction of μ-opioid receptor in the knee synovium tissue in the chronic inflammation group were significantly higher than that in the control group(P0.05).While the expression of the mRNA and the optical density(OD) of immunoreaction of μ-opioid receptor in the four parts of knee synorium tissue in each group were no significant difference(P0.05).Conclusion:The expression of μ opioid receptor in the knee joint synovium tissue in chronic inflammation was up-regulated.It might play a partial role in the peripheral mechanism of morphine." @default.
- W2362173840 created "2016-06-24" @default.
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- W2362173840 date "2008-01-01" @default.
- W2362173840 modified "2023-09-25" @default.
- W2362173840 title "THE EXPRESSION OF μ OPIOID RECEPTOR IN THE KNEE JOINT SYNOVIUM TISSUE OF THE PATIENTS WITH CHRONIC KNEE OSTEOARTHRITIS" @default.
- W2362173840 hasPublicationYear "2008" @default.
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