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- W2362176013 abstract "To determine the mechanism of RARα involvement when AP 1 activity was inhibited by all| trans retinoic acid (ATRA) in gastric cancer cells,expressions of RARα gene and cJun and cFos protein were detected by Northern blot and Western blot.AP 1 activity was measured by CAT assay,and the inhibitory rate was analyzed by MTT method.The results showed that expression of RARα was induced after treatment of gastric cancer cells with ATRA,ATRA inhibited expression of cJun and cFos,as well as AP 1 activity,which led to growth inhibition of gastric cancer cells.The data indicate that inhibition of AP 1 activity by ATRA is one of important pathway to inhibit growth of gastric cancer cells,and RARα involves in ATRA action." @default.
- W2362176013 created "2016-06-24" @default.
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- W2362176013 date "2000-01-01" @default.
- W2362176013 modified "2023-09-25" @default.
- W2362176013 title "Relationship Between AP-1 Activity and RARα Involvement in Gastric Cancer Cells" @default.
- W2362176013 hasPublicationYear "2000" @default.
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