Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362177570> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2362177570 abstract "Objective Phage particle antigens were used as a model antigen to investigate the potential mechanism of cross presentation.Methods The MHC-Ⅰ-peptide complexes formation was analyzed by FACS and cofocus technology after macrophage cells were cocultured with recombinant phage particles.Furthermore,the effect of proteasome inhibitors and TAP on particle antigens cross presentation was investigated by FACS analysis.Result The cytoplasmic MHC-Ⅰ-peptide complexes were markedly increased and reached a plateau at about 5 h after macrophage cells were cocultured with pC89hisOVA or pC89hisHa and the cross presentation of phage particles is TAP dependent.It was observed that MG132,lactacystin,and NH_4Cl markedly inhibited the formation of MHC-Ⅰ-peptide complexes.However,leupeptin or bestatin treatment did not affect the cross presentation of phage particles.Conclusion Cross presentation of phage particles is TAP dependent and sensitive to proteasome inhibitors and NH_(4)Cl." @default.
- W2362177570 created "2016-06-24" @default.
- W2362177570 creator A5014054701 @default.
- W2362177570 date "2006-01-01" @default.
- W2362177570 modified "2023-09-23" @default.
- W2362177570 title "Primary study on the mechanism of particle antigen cross presentation" @default.
- W2362177570 hasPublicationYear "2006" @default.
- W2362177570 type Work @default.
- W2362177570 sameAs 2362177570 @default.
- W2362177570 citedByCount "0" @default.
- W2362177570 crossrefType "journal-article" @default.
- W2362177570 hasAuthorship W2362177570A5014054701 @default.
- W2362177570 hasConcept C147483822 @default.
- W2362177570 hasConcept C153911025 @default.
- W2362177570 hasConcept C154317977 @default.
- W2362177570 hasConcept C159047783 @default.
- W2362177570 hasConcept C170627219 @default.
- W2362177570 hasConcept C185592680 @default.
- W2362177570 hasConcept C190062978 @default.
- W2362177570 hasConcept C202751555 @default.
- W2362177570 hasConcept C203014093 @default.
- W2362177570 hasConcept C207936829 @default.
- W2362177570 hasConcept C27740335 @default.
- W2362177570 hasConcept C2776148510 @default.
- W2362177570 hasConcept C2778367456 @default.
- W2362177570 hasConcept C2778973524 @default.
- W2362177570 hasConcept C2779281246 @default.
- W2362177570 hasConcept C55493867 @default.
- W2362177570 hasConcept C83464605 @default.
- W2362177570 hasConcept C86803240 @default.
- W2362177570 hasConceptScore W2362177570C147483822 @default.
- W2362177570 hasConceptScore W2362177570C153911025 @default.
- W2362177570 hasConceptScore W2362177570C154317977 @default.
- W2362177570 hasConceptScore W2362177570C159047783 @default.
- W2362177570 hasConceptScore W2362177570C170627219 @default.
- W2362177570 hasConceptScore W2362177570C185592680 @default.
- W2362177570 hasConceptScore W2362177570C190062978 @default.
- W2362177570 hasConceptScore W2362177570C202751555 @default.
- W2362177570 hasConceptScore W2362177570C203014093 @default.
- W2362177570 hasConceptScore W2362177570C207936829 @default.
- W2362177570 hasConceptScore W2362177570C27740335 @default.
- W2362177570 hasConceptScore W2362177570C2776148510 @default.
- W2362177570 hasConceptScore W2362177570C2778367456 @default.
- W2362177570 hasConceptScore W2362177570C2778973524 @default.
- W2362177570 hasConceptScore W2362177570C2779281246 @default.
- W2362177570 hasConceptScore W2362177570C55493867 @default.
- W2362177570 hasConceptScore W2362177570C83464605 @default.
- W2362177570 hasConceptScore W2362177570C86803240 @default.
- W2362177570 hasLocation W23621775701 @default.
- W2362177570 hasOpenAccess W2362177570 @default.
- W2362177570 hasPrimaryLocation W23621775701 @default.
- W2362177570 hasRelatedWork W1531857501 @default.
- W2362177570 hasRelatedWork W1547328769 @default.
- W2362177570 hasRelatedWork W1577004966 @default.
- W2362177570 hasRelatedWork W1604192625 @default.
- W2362177570 hasRelatedWork W1964069011 @default.
- W2362177570 hasRelatedWork W1972996100 @default.
- W2362177570 hasRelatedWork W2011541044 @default.
- W2362177570 hasRelatedWork W2017540069 @default.
- W2362177570 hasRelatedWork W2022602665 @default.
- W2362177570 hasRelatedWork W2035456059 @default.
- W2362177570 hasRelatedWork W2037392238 @default.
- W2362177570 hasRelatedWork W2040628376 @default.
- W2362177570 hasRelatedWork W2055183177 @default.
- W2362177570 hasRelatedWork W2058816119 @default.
- W2362177570 hasRelatedWork W2068329274 @default.
- W2362177570 hasRelatedWork W2088532914 @default.
- W2362177570 hasRelatedWork W2110515054 @default.
- W2362177570 hasRelatedWork W2116438738 @default.
- W2362177570 hasRelatedWork W2437170915 @default.
- W2362177570 hasRelatedWork W251057727 @default.
- W2362177570 isParatext "false" @default.
- W2362177570 isRetracted "false" @default.
- W2362177570 magId "2362177570" @default.
- W2362177570 workType "article" @default.