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- W2362190266 abstract "Objective To investigate the safety and feasibility of sevoflurane combined intravenous with inhalation anesthesia(CIIA) for nasal endoscope surgery in hypertensive patients.Methods Thirty hypertension patients without thromboasthenia undergoing selective nasal endoscope surgery(American Association of Anesthetists classify brand Ⅰ or Ⅱ) were randomly divided into two groups:group A(15 cases) and group B(15 cases).Both groups were induced by 0.05 mg/kg of midazolam,0.3 mg/kg of etomidate,0.1 mg/kg of vecuronium bromide and 4 μg/kg of fentanyl.Anesthesia was maintained in group A by using sevoflurane,propofol and vecuronium bromide,and in Group B using propofol,vecuronium bromide and fentanyl.Intraoperative sevoflurane concentration was gradually increased to objective pressure(MAP 65-75 mm Hg) in group A,and the invasive blood pressure,heart rate,respiratory carbon dioxide partial pressure at the end,electrocardiogram and peripheral pulse oxygen saturation were continuously monitored at next time points:the beginning time of the surgery(T0),the time when it went on 20 min(T1) and ten min after the surgery(T2).When the operation was over for 30 min,arterial blood was pumped to get blood gas analysis,the time of eyes-open and eyes-closed trachea cannula taking away and the total time of surgery were recorded.The respiratory depressing,lethargy,restlessness,nausea and vomiting or other untoward effects were observed.Results MAP(T1) decreased obviously as compared with it at T0(P0.01) and rose again at T2.MAP(T1) in group A decreased obviously compared with group B(P0.01).In group A,when a trachea cannula and nasal endoscope was in,hemodynamics was stable.Analepsia was very safe and quick and had no postoperative complications.But in group B,blood pressure significantly rose,recover of anesthesia was rather slow and there were nausea and vomiting(2 cases) and lethargy(3 cases).Conclusion Sevoflurane CIIA has good effects on controlling blood pressure,reducing the amount of bleeding,shortening the surgery time,making analepsia safe and quick,and having less untoward effects on hypertensive patients in nasal endoscope surgery.It can meet well anesthesia demand of patients with nasal endoscope surgery." @default.
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- W2362190266 date "2011-01-01" @default.
- W2362190266 modified "2023-09-24" @default.
- W2362190266 title "Combined Intravenous with Inhalation Sevoflurane Anesthesia for Nasal Endoscopic Surgery in Hypertensive Patient" @default.
- W2362190266 hasPublicationYear "2011" @default.
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