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- W2362192044 abstract "Objective To investigate that Mycophenolate Mofetil (MMF) potentiates anti-cytomegalovirus(CMV) activities of Ganciclovir(GCV) after kidney transplantation.Methods 187 primary cadaveric renal allograft recipients at our center from January 2004 to June 2005 were divided into two groups which included the MMF-treated group (MMF group) and the azathioprine(AZA)-treated group (AZA group) according to their immunosuppressive therapy.The incidence of CMV infection and the graft survival were compared and analysed prospectively between the two groups.Results Graft survival rate was increased significantly at 1 year in patients in the MMF group compared with those in the AZA group(73.3 versus 94.1%) but only in patients who developed CMV infection.There was no difference in graft survival rate between the two groups without CMV infection.In AZA group,the graft survival rate was lower in patients with CMV infection than those without CMV infection.Meanwhile there was no difference in the MMF group.Conclusions In patients with CMV infection,the graft survival rate at 1 year was higher in MMF group than those in AZA group.Our data indicate that MMF potentiates anticytomegalovirus activities of Ganciclovir in renal transplanted patients,but further studies should be done." @default.
- W2362192044 created "2016-06-24" @default.
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- W2362192044 date "2011-01-01" @default.
- W2362192044 modified "2023-09-26" @default.
- W2362192044 title "Mycophenolate Mofetil potentiates anti-cytomegalovirus activities of Ganciclovir and its mechanism" @default.
- W2362192044 hasPublicationYear "2011" @default.
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