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- W2362204633 abstract "Objective: To explore the effects of IL-15 and IL- 33 in pathogenesis of childhood asthma. Methods: The serum samples were obtained from 38 children with asthma during acute attack phase,25 children with asthma during clinical remission phase,and 25 children without asthma. The serum levels of IL- 15 and IL- 33 were measured by ELISA. Results: The level of IL- 15 in acute attack phase group was statistically significantly higher than those in clinical remission phase group and control group( P 0. 01). The level of IL- 15 in clinical remission phase group was statistically significantly higher than that in control group( P 0. 01),there was no statistically significant difference in serum IL- 33 level among the three groups( F = 2. 272,P 0. 05); there was no correlation between serum IL- 33 level and serum IL- 15 level in children with asthma. Conclusion: IL- 15 plays a promoting inflammation role in pathogenesis of childhood asthma,and it may play an important role in chronic persistent inflammation of airway; for IL- 33 / ST2L system,it perhaps is not IL- 33 but ST2L to control inflammation development of childhood asthma,the specific role of IL- 33 in childhood asthma remains to be further studied." @default.
- W2362204633 created "2016-06-24" @default.
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- W2362204633 date "2014-01-01" @default.
- W2362204633 modified "2023-09-23" @default.
- W2362204633 title "Study on the effects of IL-33 and IL-15 in pathogenesis of childhood asthma" @default.
- W2362204633 hasPublicationYear "2014" @default.
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