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- W2362205559 abstract "Objective To investigate expression and clinical significance of histone deacetylase 6 in gastric cancer.Methods A total of 87 patients with gastric cancer were selected in hospital from October 2011 to October 2013 as observation group.Another 83 patients with chronic inflammation of gastric mucosa were selected at the same period as control group.Histone deacetylase 6 protein and mRNA were detected by immunohistochemistry and in situ hybridization.Relationship between histone deacetylase 6 protein,mRNA and degree of histologic differentiation,invasion depth,and lymph node metastasis were analyzed.Relevance of histone deacetylase 6 protein and mRNA were analyzed.Results Positive rates of histone deacetylase 6 protein and mRNA in observation group were obviously higher than control group.Histone deacetylase 6 protein,and mRNA had obvious positive correlation with degree of histologic differentiation,invasion depth and lymph node metastasis.Histone deacetylase 6 protein had obvious positive correlation with mRNA.Conclusion Histone deacetylase 6 protein and mRNA is helpful in identifying clinical symptoms and biological behavior,which has clinical significance." @default.
- W2362205559 created "2016-06-24" @default.
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- W2362205559 date "2014-01-01" @default.
- W2362205559 modified "2023-09-24" @default.
- W2362205559 title "Expression and Clinical Significance of Histone Deacetylase 6 in Gastric Cancer" @default.
- W2362205559 hasPublicationYear "2014" @default.
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