Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362208020> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2362208020 abstract "Aim To study the effect of Semen Sojae Preparatum isoflavone(SSPI)on proliferation and JAK2/STAT3 signal transduction pathway in rat vascular smooth muscle cell(VSMC)induced by Angiotensin Ⅱ(AngⅡ).Methods A cell proliferating model of VSMC induced by AngⅡ was established.The proliferation activity of VSMC was analyzed by MTT method.The expressions of angiotensin Ⅱ receptor 1(AT1R) were detected by RT-PCR method.The expressions of JAK2,STAT3 and phosphorylation protein were detected by Western blot.Results 100 μg·L-1, 200 μg·L-1 SSPI significantly inhibited the proliferation of VSMC induced by AngⅡ,and down-regulated the mRNA expression of AT1R.200 μg·L-1 SSPI could significantly down-regulate the protein expressions of p-JAK2,p-STAT3.Conclusions The proliferation of VSMC induced by AngⅡcan be inhibited by SSPI.The mechanisms might be related to down-regulating the expressions of AT1R,and arresting the phosphorylation of JAK2/STAT3 signal transduction pathway." @default.
- W2362208020 created "2016-06-24" @default.
- W2362208020 creator A5047967535 @default.
- W2362208020 date "2009-01-01" @default.
- W2362208020 modified "2023-09-23" @default.
- W2362208020 title "Effect of Semen Sojae Preparatum isoflavone on JAK2/STAT3 signal transduction pathway in proliferated vascular smooth muscle cell" @default.
- W2362208020 hasPublicationYear "2009" @default.
- W2362208020 type Work @default.
- W2362208020 sameAs 2362208020 @default.
- W2362208020 citedByCount "0" @default.
- W2362208020 crossrefType "journal-article" @default.
- W2362208020 hasAuthorship W2362208020A5047967535 @default.
- W2362208020 hasConcept C104317684 @default.
- W2362208020 hasConcept C11960822 @default.
- W2362208020 hasConcept C126322002 @default.
- W2362208020 hasConcept C134018914 @default.
- W2362208020 hasConcept C153911025 @default.
- W2362208020 hasConcept C170493617 @default.
- W2362208020 hasConcept C185592680 @default.
- W2362208020 hasConcept C2776415932 @default.
- W2362208020 hasConcept C2778923194 @default.
- W2362208020 hasConcept C2779395532 @default.
- W2362208020 hasConcept C2908929049 @default.
- W2362208020 hasConcept C2992686903 @default.
- W2362208020 hasConcept C55493867 @default.
- W2362208020 hasConcept C62112901 @default.
- W2362208020 hasConcept C62478195 @default.
- W2362208020 hasConcept C71924100 @default.
- W2362208020 hasConcept C86803240 @default.
- W2362208020 hasConcept C95444343 @default.
- W2362208020 hasConceptScore W2362208020C104317684 @default.
- W2362208020 hasConceptScore W2362208020C11960822 @default.
- W2362208020 hasConceptScore W2362208020C126322002 @default.
- W2362208020 hasConceptScore W2362208020C134018914 @default.
- W2362208020 hasConceptScore W2362208020C153911025 @default.
- W2362208020 hasConceptScore W2362208020C170493617 @default.
- W2362208020 hasConceptScore W2362208020C185592680 @default.
- W2362208020 hasConceptScore W2362208020C2776415932 @default.
- W2362208020 hasConceptScore W2362208020C2778923194 @default.
- W2362208020 hasConceptScore W2362208020C2779395532 @default.
- W2362208020 hasConceptScore W2362208020C2908929049 @default.
- W2362208020 hasConceptScore W2362208020C2992686903 @default.
- W2362208020 hasConceptScore W2362208020C55493867 @default.
- W2362208020 hasConceptScore W2362208020C62112901 @default.
- W2362208020 hasConceptScore W2362208020C62478195 @default.
- W2362208020 hasConceptScore W2362208020C71924100 @default.
- W2362208020 hasConceptScore W2362208020C86803240 @default.
- W2362208020 hasConceptScore W2362208020C95444343 @default.
- W2362208020 hasLocation W23622080201 @default.
- W2362208020 hasOpenAccess W2362208020 @default.
- W2362208020 hasPrimaryLocation W23622080201 @default.
- W2362208020 hasRelatedWork W1977690039 @default.
- W2362208020 hasRelatedWork W1978711899 @default.
- W2362208020 hasRelatedWork W2070345591 @default.
- W2362208020 hasRelatedWork W2092426681 @default.
- W2362208020 hasRelatedWork W2106217350 @default.
- W2362208020 hasRelatedWork W2122923309 @default.
- W2362208020 hasRelatedWork W2157988179 @default.
- W2362208020 hasRelatedWork W2348617331 @default.
- W2362208020 hasRelatedWork W2352162338 @default.
- W2362208020 hasRelatedWork W2358956808 @default.
- W2362208020 hasRelatedWork W2363605165 @default.
- W2362208020 hasRelatedWork W2375983341 @default.
- W2362208020 hasRelatedWork W2390805228 @default.
- W2362208020 hasRelatedWork W2415577773 @default.
- W2362208020 hasRelatedWork W2433075639 @default.
- W2362208020 hasRelatedWork W2898927700 @default.
- W2362208020 hasRelatedWork W2984262392 @default.
- W2362208020 hasRelatedWork W2996709776 @default.
- W2362208020 hasRelatedWork W3142047920 @default.
- W2362208020 hasRelatedWork W3144615386 @default.
- W2362208020 isParatext "false" @default.
- W2362208020 isRetracted "false" @default.
- W2362208020 magId "2362208020" @default.
- W2362208020 workType "article" @default.