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- W2362254616 abstract "AIM To prepare sustained release tablets of galantamine hydrobromide and determine its dissolution profile.METHODS Orthogonal design was utilized to obtain the best formula.Glycerin Monostearate and eudragit L100-55 were used as sustained release material to prepare the sustained-release tablets and impact of their amount and the amount of talcum powder was investigated.The assay of galantamine hydrobromide was determined by UV spectrophotometric analysis and the measure of the drug release in vitro was set up according to the method of Chinese Pharmacopoeia(2005).RESULTS The sustained release tablets can continuously release for 24 h and the dissolution curves in vitro showed that the drug release could be best described by the Higuchi equation.The methods of manufacture and determination were simple also.CONCLUSION The formula of the sustained release tablets is reasonable and it is worth doing further research." @default.
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- W2362254616 date "2006-01-01" @default.
- W2362254616 modified "2023-09-27" @default.
- W2362254616 title "Preparation of Galantamine Hydrobromide Sustained Release Tablets" @default.
- W2362254616 hasPublicationYear "2006" @default.
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