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- W2362273174 abstract "Objective To analyse the effect of simvastation on defect repairing of tibia in rats. Methods Bone defects in length model of tibia in forty rats was established. All of the defects of left tibia were filled with nothing as control. The defects of right tibia were separately filled with Bio-oss only (group A), Bio-oss combined with injection of simvastatin on defect (group B), Bio-oss compounded with 2.5% simvastatin (group C), Bio-oss compounded with 15% simvastatin (group D). The rats were sacrificed in 4 and 8 weeks and the bone formation was observed in defect. Results Compared with group B and D, the repairing of defect of group C was better in bone volume and bone density and more osteoblast and less fibre tissue were found. Conclusion Simvastatin combined with bioactive material can improve healing of bone defect." @default.
- W2362273174 created "2016-06-24" @default.
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- W2362273174 date "2005-01-01" @default.
- W2362273174 modified "2023-09-23" @default.
- W2362273174 title "The Experimental Study of Effects of Simvastatin by Different Administration Ways on Defect Repairing of Tibia in Rats" @default.
- W2362273174 hasPublicationYear "2005" @default.
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