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- W2362282034 abstract "Objective To investigate the diagnostic value of PreS1 protein for HBV infection.Methods HBV-M and PreS1 were detected by enzyme-linked immunosorbent assay(ELISA),HBV-DNA by fluorescent quantitative PCR,HBeAg and HBsAg by electro chemiluminescence immunoassay(ECLIA) quantitatively.Results Positive rates of PreS1 were 91.84%,85.79%,71.01%,78.82% respectively in model 13,135,145,15.PreS1 positive rate increased with HBV-DNA level and to HBV-DNA PreS1 had high sensitivity(Se=0.81) but Sp was 0.27,kappa 0.1;moreover no statistical difference existed between PreS1 positive group and negative group in each model.PreS1 positive rate varied with HBeAg and HBsAg level and OR of HBeAg to PreS1 was 4.16.The difference had statistical significance.Positive rate of PreS1 increased with the quantity of HBsAg.Conclusion Four elements including HBV-M model,HBV-DNA,HBeAg and HBsAg had influence on PreS1,which should be considered comprehensively on making an diagnosis and treatment for HBV infection." @default.
- W2362282034 created "2016-06-24" @default.
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- W2362282034 date "2012-01-01" @default.
- W2362282034 modified "2023-09-24" @default.
- W2362282034 title "Diagnostic Value of PreS1 Protein for HBV Infection" @default.
- W2362282034 hasPublicationYear "2012" @default.
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