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- W2362291154 abstract "Objective Through the non-invasive hemodynamic monitoring system,to evaluate the hemodynamics changes of patients with obstructive sleep apnea syndrome(OSAS) and to evaluate the influence of continuous positive airway pressure(CPAP) on the hemodynamics of patients.Methods 65 patients with OSAS and 35 healthy person were selected.The non-invasive thoracic electrical bio-impedance method was used to measure the hemodynamic parameters of all the subjects.The hemodynamic parameters of patients with OSAS were reevaluated 6 and 9 months after CPAP treatment.Results Compared with patients of the control group,those of the OSAS group were significantly lower in the cardiac index [(3.8±0.8)L/(min·m2) vs(3.9±0.6)L/(min·m2)],cardiac index [(48.6±17.5)mL/m2 vs(55.4±15.9)mL/m2] and left ventricular ejection time [(280.6±103.2)ms vs(310.3±98.9)ms] values(all P 0.05);and were significantly higher in the mean arterial pressure [(100.1±20.5)mm Hg vs(90.5±15.6)mm Hg(1 mm Hg=0.133kPa)],systemic vascular resistance [(1 259.3±258.8)Dyns/cm5 vs(950.9±110.7)Dyns/cm5] and systemic vascular resistance index [(1 982.8±481.7)Dyns m2/cm5 vs(1 683.5±301.9)Dyns m2/cm5] values(all P 0.05).Compared with those before treatment,after six months of CPAP treatment,the systemic vascular resistance and systemic vascular resistance index of patients with OSAS significantly decreased(P 0.05),and after 9 months of CPAP treatment,the hemodynamic monitoring parameters of patients with OSAS all improved(all P0.05).Conclusion Patients with OSAS have systemic hemodynamic abnormalities in the early stage,which is closely related to hypoxemia.CPAP can improve the patients' hemodynamic monitoring indicators." @default.
- W2362291154 created "2016-06-24" @default.
- W2362291154 creator A5067348774 @default.
- W2362291154 date "2012-01-01" @default.
- W2362291154 modified "2023-09-26" @default.
- W2362291154 title "Influence of continuous positive airway pressure on hemodynamics of patients with obstructive sleep apnea" @default.
- W2362291154 hasPublicationYear "2012" @default.
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