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- W2362336308 abstract "Angiogenesis is a process of vascular growth which is mainly limited to the reproductive system in healthy adult animals.In mammalian,the corpus luteum is a site of intense angiogenesis.Within a short period of the corpus luteum,the angiogenesis is followed either by controlled regression of the microvascular tree in the non-fertile cycle,or maintenance and stabilisation of the new vasculature in a conceptual cycle.Therefore,the corpus luteum is a unique model system in which the cellular and molecular regulation of angiogenesis can be studied.The development of new blood vessels in the ovarian corpus luteum is essential for corpus luteum formation to guarantee the necessary supply of nutrients and hormones.At present,the study of the molecular mechanism indicated vascular endothelial growth factor has a major role in the corpus luteum,since significantly inhibitory effects on luteal angiogenesis and function are observed when its action was blocked by antagonists at specific stages of the luteal phase in vivo.Investigations of the mechanisms of vascular endothelial growth factor-dependent angiogenesis in mammalian corpus luteum will provide insights into new strategies in treatment of luteal-based infertility and methods of improving animal reproduction.Based on our previous researches,we reviewed the effect of vascular endothelial growth factor on luteal angiogenesis in livestock,in order to provide some important references for clinic researches and animal husbandry production." @default.
- W2362336308 created "2016-06-24" @default.
- W2362336308 creator A5050479872 @default.
- W2362336308 date "2011-01-01" @default.
- W2362336308 modified "2023-09-28" @default.
- W2362336308 title "Effect of Vascular Endothelial Growth Factor on Regulation of Angiogenesis during Early Luteal Development in Livestock" @default.
- W2362336308 hasPublicationYear "2011" @default.
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