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- W2362339948 abstract "Objective To study the expressions of substance P(SP) in rats with unilateral chew,and to discuss the mechanism of temporomandibular disorders.Methods Thirty Wistar male rats were randomly divided into 6 groups,including 3 experimental groups and 3 control groups,5 rats in each group.The molar of right maxillary and mandibular of rats in experimental groups were ground to the gingival level without occlusal contact.The section of disc and articular capsule underwent the immunohistological study to evaluate the expressions of SP by using SABC method.Light microscope and microscopic photo analytic software and SPSS10.0 statistical software were used.Results The areas of substance P-like immunoreac tive(SP-LI) nerve fibers in 3 experimental groups were obviously larger than those in control groups(P0.01,P0.05),but the increasing tendency in 16-week group was less than that in 10-week group and 4-week group.The increased extent in non-chewing side was much higher than that in the chewing side(P0.01).Conclusion The SP might participate in the histopathologic mechanism of temporomandibular disorders.The histopathologic changes were different between chewing side and nonchewing under the condition of unilateral mastication." @default.
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- W2362339948 date "2007-01-01" @default.
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- W2362339948 title "Changes of expressions of substance P for unilateral chew in rats" @default.
- W2362339948 hasPublicationYear "2007" @default.
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