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- W2362340881 abstract "Objective To investigate the united effect of immunosuppressant and nerve growth factor on peripheral nerve injury. Method Established peripheral nerve crush injury model, and divided into four groups, saline group(inject saline by vein), NGF group(local added nerve growth factor), immunosuppressant group(inject FK506 by tail vein), NGF + FK506 group(local added nerve growth factor and injected FK506 by tail vein). Then, observed the effect by Catwalk gait analysis system, electrophysiological test and nerve tissue pathology. Result The results of Catwalk showed that the recovery of nerve function in NGF group and FK506 group were better than saline group, but worse than NGF + FK506 group. Similarly, electrophysiological test and nerve tissue pathology also showed that the effect of NGF + FK506 group in peripheral nerve injury repair was better than other groups. Conclusion Immunosuppressant, combined with nerve growth factor can promote the repair of nerve injury, there is a synergistic effect between the two." @default.
- W2362340881 created "2016-06-24" @default.
- W2362340881 creator A5063740533 @default.
- W2362340881 date "2014-01-01" @default.
- W2362340881 modified "2023-09-23" @default.
- W2362340881 title "Research of immunosuppressants and nerve growth factor enhance the repair of peripheral nerve injury" @default.
- W2362340881 hasPublicationYear "2014" @default.
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