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- W2362420985 abstract "Objective: To observe the cooperative effect and the optimal dose of oxaliplatin(L-OHP),gemcitabine(GEM) singly or combined on hepatocellular carcinoma cell line HepG2.Methods: The human hepatocellular carcinoma cell line HepG2 was cultured with L-OHP combined with/without GEM in certain concentration gradient.MTT was used to observe the cell growth inhibition.The character of the interaction between two drugs was estimated by coefficient of drug in interaction(CDI).Results: The effect of their combination was higher than either of them alone in inhibiting growth of HepG2(P0.01).Furthermore,the combination of these two drugs had a synergistic effect.Conclusion: The combination of L-OHP and GEM can increase the effect against hepatoceullar carcinoma and reduce their dosage and toxicity." @default.
- W2362420985 created "2016-06-24" @default.
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- W2362420985 date "2010-01-01" @default.
- W2362420985 modified "2023-09-28" @default.
- W2362420985 title "A study on the repression of oxaliplatin combined with gemcitabine to hepatocellular carcinoma cell line HepG2" @default.
- W2362420985 hasPublicationYear "2010" @default.
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