Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362425802> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W2362425802 abstract "Objective To study the effect of intravenous testosterone on the small coronary arteries in castrated cholesterol-fed rabbits. Methods Thirty-five male New Zealand white rabbits were randomly allocated to 5 groups:(1)control group, (2)castrated group ,(3)small dosage(3mg/kg) intravenous testosterone and castrated group, (4)physiological dosage(6mg/kg) intravenous testosterone and castrated group, (5)large dosage(12mg/kg) intravenous testosterone and castrated group. All animals were fed with high cholesterol diet. At the end of the 12th week, the serum levels of testosterone (T), estrogen(E2), estrogen/ testosterone (E2/T) ratio were measured, and all rabbits were sacrificed by air embolism .Hearts were removed and kept in 10% formalin for a week. The ventricles were obtained for determination of the degree of arteriolosclerosis by computer image analysis system. The incidences of atherogenesis and intimal thickening and the ratio of the intimal area to total area (intimal area plus intraluminal area) and intimal/medial ratio were determined. Results The incidences of atherogenesis and intimal thickening and the ratio of the intimal area to total area (intimal area plus intraluminal area) and intimal/medial ratio were markedly more serious in groups 2,3,5 than those in groups 1 and 4 (P0.05). Conclusions Intravenous testosterone at physiological dosage (6mg/kg) has beneficial effect on vascular endothelium and can decrease the incidences of atherogenesis and intimal thickening and the ratio of the intimal area to total area and intimal/medial ratio, thus benefiting the prevention of coronary artherosclerosis." @default.
- W2362425802 created "2016-06-24" @default.
- W2362425802 creator A5056298158 @default.
- W2362425802 date "2006-01-01" @default.
- W2362425802 modified "2023-09-24" @default.
- W2362425802 title "Effects of exogenous testosterone on small coronary arteries in castrated cholesterol-fed rabbits" @default.
- W2362425802 hasPublicationYear "2006" @default.
- W2362425802 type Work @default.
- W2362425802 sameAs 2362425802 @default.
- W2362425802 citedByCount "0" @default.
- W2362425802 crossrefType "journal-article" @default.
- W2362425802 hasAuthorship W2362425802A5056298158 @default.
- W2362425802 hasConcept C126322002 @default.
- W2362425802 hasConcept C134018914 @default.
- W2362425802 hasConcept C2777164284 @default.
- W2362425802 hasConcept C2778163477 @default.
- W2362425802 hasConcept C2779279991 @default.
- W2362425802 hasConcept C2779751240 @default.
- W2362425802 hasConcept C2992686903 @default.
- W2362425802 hasConcept C71924100 @default.
- W2362425802 hasConceptScore W2362425802C126322002 @default.
- W2362425802 hasConceptScore W2362425802C134018914 @default.
- W2362425802 hasConceptScore W2362425802C2777164284 @default.
- W2362425802 hasConceptScore W2362425802C2778163477 @default.
- W2362425802 hasConceptScore W2362425802C2779279991 @default.
- W2362425802 hasConceptScore W2362425802C2779751240 @default.
- W2362425802 hasConceptScore W2362425802C2992686903 @default.
- W2362425802 hasConceptScore W2362425802C71924100 @default.
- W2362425802 hasLocation W23624258021 @default.
- W2362425802 hasOpenAccess W2362425802 @default.
- W2362425802 hasPrimaryLocation W23624258021 @default.
- W2362425802 hasRelatedWork W1994272608 @default.
- W2362425802 hasRelatedWork W2010142891 @default.
- W2362425802 hasRelatedWork W2115558333 @default.
- W2362425802 hasRelatedWork W2160822149 @default.
- W2362425802 hasRelatedWork W2350338458 @default.
- W2362425802 hasRelatedWork W2350820088 @default.
- W2362425802 hasRelatedWork W2355423586 @default.
- W2362425802 hasRelatedWork W2360853743 @default.
- W2362425802 hasRelatedWork W2361282839 @default.
- W2362425802 hasRelatedWork W2364053454 @default.
- W2362425802 hasRelatedWork W2365396355 @default.
- W2362425802 hasRelatedWork W2369298881 @default.
- W2362425802 hasRelatedWork W2370055185 @default.
- W2362425802 hasRelatedWork W2370369376 @default.
- W2362425802 hasRelatedWork W2372002631 @default.
- W2362425802 hasRelatedWork W2375399894 @default.
- W2362425802 hasRelatedWork W2376736725 @default.
- W2362425802 hasRelatedWork W2380356007 @default.
- W2362425802 hasRelatedWork W2390157862 @default.
- W2362425802 hasRelatedWork W2472561569 @default.
- W2362425802 isParatext "false" @default.
- W2362425802 isRetracted "false" @default.
- W2362425802 magId "2362425802" @default.
- W2362425802 workType "article" @default.