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- W2362457341 abstract "Objective To investigate the expressions of insulin like growth factor binding protein-3(IGFBP-3)in serum and bronchoalveolar lavagae fluids(BALF)of patients with non-small cell lung cancer,and explore the clinical significance in dignosis and prognosis of lung cancer.Methods The bronchoalveolar lavagae fluids(BALF)were collected by bronchoscopy in 80 cases with non-small cell lung cancer and 14 healthy subjects.The expression of IGFBP-3 in serum and BALF were detected by immunoradioassay.Results The expression of IGFBP-3 in serum and BALF of lung cancer group were significantly lower than that of health group(P0.05).IGFBP-3 levels were significantly lower in those patients with lymphoid node metastasis or metastasis or TNMⅢ-TNMⅣ than those without metastasis or TNMⅠ-TNMⅡ(P0.05).In lung cancer group,the levels of the IGFBP-3 in serum and BALF had a significantly positive correlation(r=0.415,r=0.355,P0.01).Conclusion The IGFBP-3 may play an important role in the development of non-small cell lung cancer and is valuable in dignosis and prognosis of lung cancer." @default.
- W2362457341 created "2016-06-24" @default.
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- W2362457341 date "2008-01-01" @default.
- W2362457341 modified "2023-09-24" @default.
- W2362457341 title "Clinical significance of insulin like growth factor binding protein 3 in patients with lung cancer" @default.
- W2362457341 hasPublicationYear "2008" @default.
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